Geographic Information System (GIS) is an important tool for hydrological geology research, and its application in hydrogeology field is one of the hot issues in groundwater research. The latest application of GIS to groundwater was introduced from seven aspects: groundwater resources evaluation, groundwater resources management, land subsidence, groundwater quality evaluation and pollutants analysis, hydrogeology survey, groundwater protection, and the combination of GIS and numerical simulation technology. At the same time, problems of GIS application in the field of hydrogeology were presented, and the development of GIS in hydrogeology field was discussed. In the future, what should be strengthened includes the integration of GIS and groundwater model and distributed hydrological model, the visualization of 3D or 4D groundwater system based on GIS, the application of web GIS technology and the establishment of comprehensive systems for water resources management and evaluation in a basin.